Therapeutic Indication

Type 2 Diabetes

Details：

As an adjunct to adequate dietary management, Glucophage 500 mg is an oral antidiabetic agent (biguanide) intended for the treatment of adult diabetes.
In some cases, it may be used in association with insulin.
A reduction of diabetic complication has been shown in overweight type 2 diabetic patients treated with metformin as first-line therapy after diet therapy.

Pharmaceutical Form

Apperance

Film-coated tablet. White, circular, convex film-coated tablets.

Health Insurance Code

Glucophage Tablets 500mg：BC071521G0

License

衛署藥輸字第007152號 (500毫克)

Qualitative and Quantitative Composition

One film-coated tablet contains 500 mg metformin hydrochloride corresponding to 390 mg metformin base.

Dose and Administration

The dosage of Glucophage 500 mg is determined by doctor on an individual basis according to the results of laboratory blood glucose measurement. In general, the average dosage is 2 tablets per day (taken with or after meals). Oral route. Swallow the tablets without chewing during or at the end of meals.
Glucophage must be taken daily without interruption, except if specifically indicated by doctors.
If patient has forgotten to take a Glucophage 500 mg film-coated tablets: Take the next dose at the usual time.
Do not double the dose of Glucophage 500 mg film-coated tablets.
If patient has taken more Glucophage 500 mg film-coated tablets than indicated: Consult doctor or pharmacist immediately.

Contraindications

Hypersensitivity to metformin hydrochloride or to any of the excipients.
Diabetic ketoacidosis, diabetic pre-coma.
Renal failure or reual dysfunction (creatinine clearance <60 ml/min).
Acute conditions with the potential to alter renal function such as: dehydration, severe infection, shock, intravascular administration of iodinated contrast agents.
Acute or chronic disease which may cause tissue hypoxia such as: cardiac or respiratory failure, recent myocardial infarction, shock.
Major surgery.
Hepatic insufficiency, acute alcohol intoxication, alcoholism.
Lactation.

Other precautions:

All patients should continue their diet with a regular distribution of carbohydrate intake during the day.
Overweight patients should continue their energy-restricted diet.

The usual laboratory tests for diabetes monitoring should be performed regularly.

Metformin hydrochloride alone does not cause hypoglycaemia, but caution is advised when it is used in combination with insulin or sulfonylureas.