Therapeutic Indication

Type 2 Diabetes

Details：

As an adjunct to adequate dietary management, Glucophage 1000 mg is an oral antidiabetic agent (biguanide) intended for the treatment of adult diabetes.
In some cases, it may be used in association with insulin.
A reduction of diabetic complication has been shown in overweight type 2 diabetic patients treated with metformin as first-line therapy after diet therapy.

Pharmaceutical Form

Apperance

Film-coated tablet. White, oval, biconvex film-coated tablets with a score line on both sides with "1000" engraved on one side. The tablet can be divided into equal halves

Health Insurance Code

Glucophage Tablets 1000mg：BC241891G0

License

衛署藥輸字第024189號 (1000毫克)

Qualitative and Quantitative Composition

One film-coated tablet contains
1000 mg metformin hydrochloride corresponding to 780 mg metformin base

Dose and Administration

The dosage of Glucophage 1000 mg is determined by doctor on an individual basis according to the results of laboratory blood glucose measurement. In general, the average dosage is 2 tablets per day (taken with or after meals). Oral route. Swallow the tablets without chewing during or at the end of meals.

Glucophage must be taken daily without interruption, except if specifically indicated by doctors.

If patient has forgotten to take a Glucophage 1000 mg film-coated tablets: Take the next dose at the usual time.
Do not double the dose of Glucophage 1000 mg film-coated tablets.

If patient has taken more Glucophage 1000 mg film-coated tablets than indicated: Consult doctor or pharmacist immediately.

Contraindications

Hypersensitivity to metformin hydrochloride or to any of the excipients.
Diabetic ketoacidosis, diabetic pre-coma.
Renal failure or reual dysfunction (creatinine clearance <60 ml/min).
Acute conditions with the potential to alter renal function such as: dehydration, severe infection, shock, intravascular administration of iodinated contrast agents.
Acute or chronic disease which may cause tissue hypoxia such as: cardiac or respiratory failure, recent myocardial infarction, shock.
Major surgery.
Hepatic insufficiency, acute alcohol intoxication, alcoholism.
Lactation.

Other precautions:
All patients should continue their diet with a regular distribution of carbohydrate intake during the day.
Overweight patients should continue their energy-restricted diet.

The usual laboratory tests for diabetes monitoring should be performed regularly.

Metformin hydrochloride alone does not cause hypoglycaemia, but caution is advised when it is used in combination with insulin or sulfonylureas.